chorionic trophoblast meaning in English
绒膜滋养层
Examples
- Main resuits and conclusions are as follows : 1 . after 3 days in culture , some of the chorionic trophoblast clustered together and formed mulh - nuclei syncghotrophoblast cells
主要实验结果和结论如下1免疫组织化学染色显示， 11p叫和gr免疫活性样物质存在于培养的绒毛膜滋养层细胞 - However , whether glucocothcoids modulate llp - hsd1 expression through a prgnoter dependent mechanism has never been studied . in this study we bo exainined whether 1l9 - hsdl and gr are co - expressed in the sarne chorionic trophoblast
胎盘中两型酶均存在， 11 - hsd1主要存在于胎膜的绒毛膜滋养层细胞，而11 - hsd2主要存在于胎盘的合体滋养层细胞。 - Which may provide the molecular basis for the inberine regulation of ll p - hsdl expression by glucocorticoids . secondiy , the regulation of l l 9 - hsdl expression and redutase activity by glucocorticoids was investigated in the primny cultured human chorionic trophoblast
整个妊娠过程中胎盘11 - hsd活性以氧化酶为主，使母体gc在进入胎儿循环前大部分被转化为无活性的17 -羟- 11 -脱氢皮质酮，保证胎儿正常发育所需的激素浓度。 - L lp - hsdl ma of i . 5kb was detected in the rna extracted from cult ' ured chorionic trophoblast using northem blot hybridhation method . the expression of ll6 - hsdl wa was induced by treating the chorionic cells with dexamethasone ( l0 - ' , l0 ' m ) for 24h , and the induction was blocked by co - treatinent of the cells with ru486 . these results suggest a gr - mediated effect of glucocorticoid on the rnrna expression and reductase activity of l l 9 - hsd1
人h合成的肌?一加x门’ m ）对培养的绒毛膜滋养层细胞的11p hsdi还原酶活性具有诱导作用，此诱导作用可以被gr阻断剂ru486门0川）所阻断； northern印迹杂交方法进一步证实， dex亦可诱导绒毛膜滋养层细胞11p叫inrna的表达，此诱导作用也可以被ru486门0叫川）所阻断 - The co - expression of l l6 - hsd1 and gr in the saxne chorionic trophoblast suggests possible intrcrine achons ofglucoconicoid generated by l l6 - hsdl within the cells . 2 . ewe radiomctric conversion assay showed that trctrient of the cells with the synthetic glucocorticoid - - dexarnethasone ( l0 - ' m ) for 24h increased the conversion of conisone to cortisol , and thes increase was blocked by the gr antagonist ru486
双标免疫组织化学染色结果显示11p hsdi和gr共存于同一个滋养层细胞，提示在体内无活性的gc代谢产物?一17羟d脱氢皮质酮经11p hsdi还原活化后可以直接与同一个细胞内的gr结合，即以内在分泌（ intracrine ）形式发挥作用